+1 (860) 598-0955
The TANGO2 Hotline provides life-saving consultation to clinicians treating patients with TANGO2 Deficiency Disorder (TDD). This includes patients that are hospitalized, currently in crisis, or at risk of crisis.
Meet the TANGO2 Team at Texas Children’s Hospital
The TANGO2 Team at Texas Children’s Hospital is a dedicated group of physicians, researchers, and healthcare professionals working to advance the understanding, diagnosis, and treatment of TANGO2 Deficiency Disorder(TDD). Through clinical care, research, and collaboration, our goal is to improve outcomes and quality of life for individuals affected by TDD.
Leadership & Research
Christina Y. Miyake, MD, MS
Director, Cardiovascular Genetics Arrhythmia Program
Associate Professor, Baylor College of Medicine
Dr. Miyake is a pediatric electrophysiologist specializing in genetic arrhythmias. She was part of the team to first describe TDD, is a global expert, and serves as a consultant for TDD worldwide. She leads the TANGO2 Natural History Study, which aims to understand the course of the disease and find ways to better support patients.
Seema R. Lalani, MD
Professor, Department of Molecular and Human Genetics, Baylor College of Medicine
Dr. Lalani is a clinical geneticist specializing in pediatric genetic disorders. She was one of the first researchers to describe TDD and continues to play a key role in characterizing its genetic and clinical presentation. Her work advances diagnosis, research, and family support initiatives.
Maria Jose Arredondo Sancristobal, MD
Natural History Study Coordinator, Texas Children’s Hospital
Dr. Arredondo coordinates the TANGO2 Natural History Study, managing patient recruitment, data collection, and logistics to ensure seamless collaboration between families, clinicians, and researchers.
Julissa Castro Lorenzo, MD
Research Coordinator III, Texas Children’s Hospital
Dr. Castro supports the coordination of the TANGO2 Natural History Study, facilitating data collection and ensuring adherence to research protocols. Her work is essential in optimizing communication between the clinical team and study participants.
Neurology & Neuropsychology
Kimberly Houck, MD
Assistant Professor, Pediatrics - Neurology & Neurophysiology, Baylor College of Medicine
Dr. Houck is a pediatric neurologist who evaluates and treats seizures, movement disorders, and developmental delays in patients with TDD.
Mariam Hull, MD
Assistant Professor, Baylor College of Medicine
Dr. Hull is a pediatric neurologist who specializing in movement disorders in TDD and works with the team to recognize and treat using a personalized treatment strategy.
David Daniel Schwartz, PhD
Professor, Department of Pediatrics, Psychology Division, Baylor College of Medicine
Dr. Schwartz is a pediatric neuropsychologist whose expertise is in evaluating neurodevelopment, cognitive and psychological changes that can occur in TDD. He will work with patients to assess their current status and follow their course and outcomes over time. He can provide support for cognitive and behavioral challenges.
Genetics & Metabolism
Kevin E. Glinton, MD, PhD
Assistant Professor, Department of Molecular and Human Genetics, Baylor College of Medicine
Dr. Glinton is a geneticist specializing in inborn errors of metabolism, working to identify metabolic dysfunction in TDD and improve treatment strategies.
Endocrinology
Alfonso Hoyos-Martinez, MD, FAAP
Assistant Professor, Division of Endocrinology and Diabetes, Baylor College of Medicine
Dr. Hoyos-Martinez is a pediatric endocrinologist focused on the effects specifically in the TDD patients. He identifies and manages hypothyroidism, hormones, and development in TDD.
Rehabilitation
Cosmo Kwok, MD
Assistant Professor, Physical Medicine and Rehabilitation, Baylor College of Medicine
Dr. Kwok is a pediatric rehabilitation specialist who develops personalized therapy plans to maximize mobility and functional independence in children with TDD. He assess children and young adults with TDD and has built an expertise in assessing and addressing their rehabilitation needs.
Nutrition
Nourhan Suleiman, RD, LD
Registered Dietitian, Texas Children’s Hospital
Nourhan provides personalized nutrition plans to support metabolic health and overall well-being in patients with TDD.
Pharmacy
Katherine Lemming, PharmD
Clinical Pharmacy Specialist, Texas Children’s Hospital
Katherine is a pediatric pharmacy specialist who ensures safe and effective medication management for patients with TDD, optimizing treatment plans to improve outcomes.